Which uterine tumor is considered estrogen-dependent but not precancerous?

Which uterine tumor is considered estrogen-dependent but not precancerous?

• A. Leiomyoma
• B. Endometrial carcinoma
• C. Polyps
• D. Fibromatosis

Answer: (A)

Leiomyomas, also known as uterine fibroids, are benign tumors of smooth muscle origin found in the uterus. They are well-known to be estrogen-dependent, meaning their growth is influenced by estrogen levels in the body. Estrogen promotes proliferation of smooth muscle cells, which contributes to the development and enlargement of these tumors. Importantly, while leiomyomas can cause symptoms due to their size or location, such as heavy menstrual bleeding or pelvic pain, they are not considered precancerous. This differentiates them from other uterine lesions, such as endometrial carcinoma, which is a malignant tumor and indeed a cancerous condition. In contrast to leiomyomas, endometrial carcinoma arises from the lining of the uterus and is associated with abnormal proliferation and changes in the endometrial tissue that can lead to cancer. Cervical and endometrial polyps may also be present in the uterus and can be related to excess estrogen; however, their status as benign does not exempt them from being associated with certain risks for cancer, primarily if they have atypical features. Lastly, fibromatosis, while potentially related in terms of growth patterns, is not a standard term used to describe uterine tumors and may refer to a

Leiomyomas, also known as uterine fibroids, are benign tumors of smooth muscle origin found in the uterus. They are well-known to be estrogen-dependent, meaning their growth is influenced by estrogen levels in the body. Estrogen promotes proliferation of smooth muscle cells, which contributes to the development and enlargement of these tumors.

Importantly, while leiomyomas can cause symptoms due to their size or location, such as heavy menstrual bleeding or pelvic pain, they are not considered precancerous. This differentiates them from other uterine lesions, such as endometrial carcinoma, which is a malignant tumor and indeed a cancerous condition. In contrast to leiomyomas, endometrial carcinoma arises from the lining of the uterus and is associated with abnormal proliferation and changes in the endometrial tissue that can lead to cancer.

Cervical and endometrial polyps may also be present in the uterus and can be related to excess estrogen; however, their status as benign does not exempt them from being associated with certain risks for cancer, primarily if they have atypical features. Lastly, fibromatosis, while potentially related in terms of growth patterns, is not a standard term used to describe uterine tumors and may refer to a