Which condition presents with findings of glomerular hypercellularity?

Which condition presents with findings of glomerular hypercellularity?

• A. Acute glomerulonephritis
• B. Chronic kidney disease
• C. Nephrotic syndrome
• D. Hypertensive nephrosclerosis

Answer: (A)

Glomerular hypercellularity is a hallmark finding associated with acute glomerulonephritis. In this condition, there is an inflammatory response typically triggered by an immune-mediated injury to the glomeruli, often following infections such as post-streptococcal glomerulonephritis. This inflammatory process leads to the proliferation of glomerular cells, including mesangial cells and endothelial cells, resulting in an increased number of cells in the glomeruli. Additionally, acute glomerulonephritis often presents with other characteristic features such as hematuria, proteinuria, and the presence of red blood cell casts. The hypercellularity can be identified histologically, which helps differentiate it from other renal pathologies. In contrast, chronic kidney disease typically involves glomerular scarring and a decrease in cell density, with fibrosis being a predominant feature. Nephrotic syndrome is characterized by significant proteinuria and edema, but it often presents with podocyte injury rather than hypercellularity of the glomeruli. Hypertensive nephrosclerosis is associated with changes due to chronic hypertension, such as hyaline arteriosclerosis and glomerular sclerosis, rather than hypercellularity. Thus, the presence of glomer

Glomerular hypercellularity is a hallmark finding associated with acute glomerulonephritis. In this condition, there is an inflammatory response typically triggered by an immune-mediated injury to the glomeruli, often following infections such as post-streptococcal glomerulonephritis. This inflammatory process leads to the proliferation of glomerular cells, including mesangial cells and endothelial cells, resulting in an increased number of cells in the glomeruli.

Additionally, acute glomerulonephritis often presents with other characteristic features such as hematuria, proteinuria, and the presence of red blood cell casts. The hypercellularity can be identified histologically, which helps differentiate it from other renal pathologies.

In contrast, chronic kidney disease typically involves glomerular scarring and a decrease in cell density, with fibrosis being a predominant feature. Nephrotic syndrome is characterized by significant proteinuria and edema, but it often presents with podocyte injury rather than hypercellularity of the glomeruli. Hypertensive nephrosclerosis is associated with changes due to chronic hypertension, such as hyaline arteriosclerosis and glomerular sclerosis, rather than hypercellularity. Thus, the presence of glomer