What condition occurs due to decreased conversion of Beta-carotenes into retinoic acid in the intestine?

What condition occurs due to decreased conversion of Beta-carotenes into retinoic acid in the intestine?

• A. Beta-thalassemia
• B. Beta-carotenemia
• C. Retinol excess syndrome
• D. Retinal detachment

Answer: (B)

Beta-carotenemia arises from the body's inability to convert beta-carotene into retinoic acid due to decreased enzymatic activity. In this condition, excess beta-carotene accumulates in the body, leading to yellowing of the skin, particularly on the palms and soles, without affecting the sclera. This is a benign condition and is mainly a result of diets excessively high in beta-carotene, usually from fruits and vegetables. Retinoic acid is a metabolite of vitamin A (retinol) that is crucial for vision, immune function, and cellular differentiation. If the conversion from beta-carotene to retinoids is diminished, it can result in reduced levels of retinoic acid, which may affect various physiological processes. Conditions such as beta-thalassemia, retinol excess syndrome, and retinal detachment are not directly related to the metabolism of beta-carotene, making beta-carotenemia the most suitable answer in this context.

Beta-carotenemia arises from the body's inability to convert beta-carotene into retinoic acid due to decreased enzymatic activity. In this condition, excess beta-carotene accumulates in the body, leading to yellowing of the skin, particularly on the palms and soles, without affecting the sclera. This is a benign condition and is mainly a result of diets excessively high in beta-carotene, usually from fruits and vegetables.

Retinoic acid is a metabolite of vitamin A (retinol) that is crucial for vision, immune function, and cellular differentiation. If the conversion from beta-carotene to retinoids is diminished, it can result in reduced levels of retinoic acid, which may affect various physiological processes.

Conditions such as beta-thalassemia, retinol excess syndrome, and retinal detachment are not directly related to the metabolism of beta-carotene, making beta-carotenemia the most suitable answer in this context.